OBJECTIVE: The study aimed to determine the levels of bone turn over biomarker (ALP) in Iraqi acromegaly patients in addition to find the relationship between these levels in serum and saliva. METHODS: In this cross-sectional study, 20 healthy controls (10 female and 10 male) and 40 patients with acromegaly (22 female and 18 male) who were visiting the National Centre for Diabetes and Endocrinology / AL- Mustansiriya University / Baghdad were included. Every patient was prescribed an octreotide somatostatin analog medication after being diagnosed by a hospital doctor. For both groups, the levels of alkaline phosphatase (ALP) in serum and saliva were measured. RESULTS: The acromegaly group had higher mean values of serum and salivary ALP than the control group (p=0.01, p


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