Does Insulin Resistance (IR) Have an Impact on The Reproductive and Fertility Potential in Polycystic Ovary Syndrome (PCOS) Women? : Review Article

Authors

Muhjah Falah Hassan, Department of Anatomy, Histology and Embryology, Faculty of Medicine, Kerbala University/IraqFollow
Mufedah Ali Jawad, High Institute of Infertility Diagnosis and Assisted Reproductive Technologies/AL-Nahrain University/Iraq
Rabab Zahir Al-yasiry, Department of Anatomy and Histology, Faculty of Medicine, Babylon University/ Iraq

Abstract

Backgrounds: Polycystic ovary syndrome is the most common endocrine and reproductive disorder in the reproductive-age women. Among the pathological changes that are responsible for the development of polycystic ovary syndrome (PCOS), hyperinsulinemia due to increased insulin resistance (IR) is common and usually associated with a higher rate of ovulatory dysfunction and sub-fertility. In addition, those women have poor quality oocytes with low fertilization capability and poor quality embryos. So, insulin has a role in the reproductive function and fertility potential of reproductive age women. Conclusion: Females with PCOS usually exhibit an extreme difficulty in achieving either a successful spontaneous or assisted pregnancy. Hyperinsulinemia / insulin resistance and reproductive dysfunction should be well understood as can as possible in order to achieve an effective treatment plan to increase the chance of a successful uncomplicated pregnancy.

Recommended Citation

Hassan, Muhjah Falah; Jawad, Mufedah Ali; and Al-yasiry, Rabab Zahir (2023) "Does Insulin Resistance (IR) Have an Impact on The Reproductive and Fertility Potential in Polycystic Ovary Syndrome (PCOS) Women? : Review Article," Maaen Journal for Medical Sciences: Vol. 2 : Iss. 1 , Article 3.
Available at: https://doi.org/10.55810/2789-9136.1014

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